Preliminary study on phenotype and genotype of antibiotic resistance in Salmonella enterica subsp. enterica serotype Typhimurium Isolated from Chicken Samples in Malaysia

Salmonellosis is a significant public health concern around the world. The issue of antibiotic resistance, particularly in non-typhoidal Salmonella (NTS), global threat to human and animal health. Thirty-five enterica subsp. serotype Typhimurium (S. Typhimurium) isolated from various chicken samples were tested for antimicrobial-resistant profiling using disc diffusion method. strains further examined presence resistance genes by polymerase chain reaction (PCR) according published protocols. Phenotype revealed that 22.9% (8 out 35) isolates showed five antibiotics used this study. All penta-resistant carried blaTEM, floR, strA, tetA gene which encoded ampicillin, chloramphenicol, streptomycin, tetracycline resistance. Only one isolate (1 was found contain sulfonamides sulA gene. Nine susceptible all do not harbor any resistant associated genes. These findings provide evidence contributes phenotypic profile, thus could give rise emergence drug-resistant strain Salmonella.